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The ketogenic diet plan is gender sensitive


A scholarly research conducted in mice implies that the effects of the diet, which suppresses nearly all carbohydrates towards body fat, vary according to… the sex of the eater.

A fashionable diet plan, the ketogenic diet plan, where the most carbohydrates (sugars) are suppressed towards lipids (fats), is meant to have slimming properties. The principle is, theoretically, basic: deprived of the energy normally supplied by carbohydrates, your body “burns” unwanted fat by transforming it. But its hazards are a lot more certain in human beings than its virtues. And a fresh study seems to display that its results vary regarding to… the sex of the eater.

A group from the University of Iowa investigated the result on mice of a diet plan composed of 75% body fat, 3% carbohydrate and 8% protein (in comparison to 7%, 47% and 19% in a standard diet). And they discovered that the fat burning capacity of females was much less responsive than that of men. The task was presented at the ultimate end of March at the congress of the American Culture of Endocrinology.

Females on the ketogenic diet plan gained more excess weight after 15 weeks than those on normal diet plans and had poorer blood sugar control; heavily-nourished men lost fat and fasting blood sugar were less than those on a typical diet.

“There are significant gender differences in body composition and fat burning capacity in response to the ketogenic diet plan, which can be related to estrogens partially.”

Suspecting estrogens to lead to these differences, the protocol was repeated by the authors with females deprived of their ovaries. Those on ketogenic diet plans then lost fat and fat, but still had difficulty controlling their sugar levels. Summary of the authors: “There are significant gender variations in body composition and rate of metabolism in response to the ketogenic diet, which can be partially attributed to estrogens.

“Our discovery suggests that postmenopausal women may achieve better weight loss with the ketogenic diet than younger ladies,” said Jesse Cochran, the principal investigator. In a statement, the President of the Society of Endocrinology E. Dale Abel recommends consulting a doctor before following this type of diet. Because in addition to disturbing effects (nausea, constipation, fatigue…) and the risk of an excess weight gain upon returning to a normal diet, the ketogenic diet can lead to deficiencies, hypercholesterolemia, “fatty liver”, kidney stones, osteoporosis… “Man is programmed for balanced and omnivorous diet programs”, Professor Luc Cynober, head of the biochemistry division at Cochin Hospital (AP-HP) recently insisted on our site.

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